Could Ketamine Therapy Help Your Depression?

For people who haven't responded to traditional antidepressants, ketamine therapy is offering new hope. Learn what the research says and how to find treatment.

How It Works Find a Clinic Near You

What You Need to Know About Ketamine Therapy

Ketamine is one of the most significant breakthroughs in depression treatment in decades.

Fast Acting

Unlike traditional antidepressants that take weeks to work, ketamine can reduce depression symptoms within hours or days for many patients.

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Research Backed

Decades of clinical research support ketamine's effectiveness for treatment-resistant depression, PTSD, and chronic pain conditions.

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Medical Supervision

Ketamine therapy is administered in a clinical setting by licensed medical professionals, ensuring safety and proper dosing.

What is Treatment-Resistant Depression?

Millions of people with depression don't respond to standard antidepressants. Ketamine therapy was specifically developed to help people in this situation. Learn who it's designed for and how it works differently from traditional treatments.

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Common Questions About Ketamine Therapy

Get the facts before you decide if ketamine treatment is right for you.

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Is It FDA Approved?

Esketamine (Spravato), a nasal spray form of ketamine, received FDA approval for treatment-resistant depression in 2019. IV ketamine is used off-label.

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How Much Does It Cost?

IV ketamine infusions typically cost $400–$800 per session. Most patients require 6 sessions. Insurance coverage is improving but still limited.

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How Long Does It Last?

Results vary. Some patients experience relief for weeks or months after a series of infusions. Many choose maintenance infusions over time.

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Is It Safe?

When administered in a clinical setting by trained professionals, ketamine therapy has a strong safety record. Side effects are typically mild and short-lived.

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How Does It Work?

Ketamine works differently from SSRIs. It acts on NMDA receptors in the brain, rapidly creating new neural connections that can lift depression quickly.

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Where Can I Get It?

Ketamine clinics exist in most major US cities. Treatment is also available through some psychiatrists, anesthesiologists, and telehealth providers.

Ready to Learn More?

Read our complete guide to ketamine therapy for depression — including how it works, what to expect, and how to find a reputable clinic near you.

What is Ketamine Therapy? Find a Clinic